Anna Lisa Fear

US Patent:

58661140, Feb 2, 1999

Filed:

May 25, 1995

Appl. No.:

8/351292

Inventors:

Jayvardhan Pandit - Mystic CT
Jarmila Jancarik - Walnut Creek CA
Kirston Koths - El Cerrito CA
Robert Halenbeck - San Rafael CA
Anna Lisa Fear - Oakland CA
Eric Taylor - Oakland CA
Ralph Yamamoto - Martinez CA
Andrew Bohm - Berkeley CA

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

A61K 3819

US Classification:

424 851

Abstract:

The present invention is directed to methods for crystallizing macrophage colony stimulating factor (M-CSF) and to a crystalline M-CSF produced thereby. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.

US Patent:

52682749, Dec 7, 1993

Filed:

Apr 22, 1991

Appl. No.:

7/689008

Inventors:

Arie Ben-Bassat - Walnut Creek CA
Roger D. Calhoon - Concord CA
Anna L. Fear - Oakland CA
David H. Gelfand - Oakland CA
James H. Meade - Pinole CA
Rony Tal - Richmond CA
Hing Wong - San Ramon CA
Moshe Benziman - Jerusalem, IL

Assignee:

Cetus Corporation - Emeryville CA

International Classification:

C12N 1500
C12N 1554
C12N 1574
C12P 1904

US Classification:

435 691

Abstract:

Nucleic acid sequences encoding the bacterial cellulose synthase operon derived from Acetobacter are disclosed. Methods for isolating the genes, vectors containing the genes, and transformed hosts useful for the expression of recombinant bacterial cellulose synthase or production of cellulose are also described.

US Patent:

60251468, Feb 15, 2000

Filed:

Jun 5, 1995

Appl. No.:

8/462069

Inventors:

Jayvardhan Pandit - Mystic CT
Jarmila Jancarik - Walnut Creek CA
Kirston Koths - El Cerrito CA
Robert Halenbeck - San Rafael CA
Anna Lisa Fear - Oakland CA
Eric Taylor - Oakland CA
Ralph Yamamoto - Martinez CA
Andrew Bohm - Armonk NY

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

G01N 3353

US Classification:

435 72

Abstract:

The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.