Anilkumar R Kore from 8321 Pommel Dr, Austin, TX 78759, age 55, Phone: 5122208583

Us Patents

Preparation And Isolation Of 5′ Capped Mrna
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US Patent:

8093367, Jan 10, 2012
Filed:

Apr 30, 2010
Appl. No.:

12/771495
Inventors:

Anilkumar Kore - Austin TX, US
Shanmugasundaram Muthian - Austin TX, US
Irudaya Charles - Austin TX, US
Assignee:

Applied Biosystems, LLC - Carlsbad CA
International Classification:

C07H 21/02
C07H 21/00
C07H 19/04
C12N 5/00
G01N 15/06
C12Q 1/68
US Classification:

536 231, 536 253, 536 266, 435 6, 435325, 422 681
Abstract:

The synthesis of capped/tagged RNA, methods of use and kits providing same are contemplated. Tagged RNA permits isolation of RNA transcripts in vitro. The ability to isolate and purify capped RNA results in improved transcription and translation and provides a tool for identifying RNA-protein interactions. Such capped RNA finds use in therapeutic applications, diagnosis and prognosis and in the treatment of cancers and HIV.

5-Bromo-2′-Deoxy-Uridine Labeled Nucleotide Triphosphates And Nucleic Acid Probes And Methods Of Making And Using The Same
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US Patent:

8163897, Apr 24, 2012
Filed:

Mar 1, 2011
Appl. No.:

13/038184
Inventors:

Anilkumar R. Kore - Austin TX, US
Zhongting Hu - Los Angeles CA, US
Assignee:

Applied Biosystems, LLC - Carlsbad CA
International Classification:

C07H 21/00
C12Q 1/68
C07H 21/02
C12P 19/34
B01L 3/00
US Classification:

536 253, 536 231, 536 243, 435 6, 435 911, 422 61
Abstract:

5-bromo-2′-deoxy-uridine (BrdU) labeled nucleotide triphosphates and nucleic acid probes are described herein. The BrdU labeled nucleotide triphosphates include a linker between the nucleotide triphosphate and the BrdU moiety. The linker can be cleavable or non-cleavable. The nucleotide triphosphates can be a ribonucleotide triphosphates, 2′-deoxyribonucleotide triphosphates or 2′,3′-dideoxyribonucleotide triphosphates. The nucleic acid probes can be used for in situ hybridization.

Proteinase K Inhibitors, Methods And Compositions Therefor
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US Patent:

8211637, Jul 3, 2012
Filed:

Dec 18, 2009
Appl. No.:

12/642322
Inventors:

Anilkumar R. Kore - Austin TX, US
Muthian Shanmugasundaram - Austin TX, US
Assignee:

Life Technologies Corporation - Carlsbad CA
International Classification:

C12Q 1/68
US Classification:

435 61, 435 612, 514 219, 530330
Abstract:

The synthesis, biological evaluation, and molecular modeling of alkoxysuccinyl-peptidyl-haloalkyl ketones for use as proteinase K inhibitors are described. Sample preparation processes for in situ RNA or DNA analysis using such inhibitors, methods and compositions therefor are provided.

Dinucleotide Mrna Cap Analogs
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US Patent:

8304529, Nov 6, 2012
Filed:

Jul 10, 2007
Appl. No.:

12/375527
Inventors:

Anilkumar R. Kore - Austin TX, US
Muthian Shanmugasundaram - Austin TX, US
Assignee:

Life Technologies Corporation - Carlsbad CA
International Classification:

C07H 21/00
US Classification:

536 253, 536 231, 536 261, 536 262, 536 2621, 536 2622, 514 43, 514 45, 514 46, 514 47
Abstract:

Novel cap analogs which are easily synthesized, resulting in high levels of capping efficiency and transcription and improved translation efficiencies are provided. Such caps are methylated at the N7 position of one or both guanosines of the dinucleotide cap as well as at the 3′ position on the ribose ring. Substituent groups on the ribose ring also result in the cap being incorporated in the forward orientation. Also provided are methods useful for preparing capped analogs and using mRNA species containing such analogs are also contemplated herein, as well as kits containing the novel cap analogs.

Preparation And Isolation Of 5′ Capped Mrna
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US Patent:

8344118, Jan 1, 2013
Filed:

Dec 13, 2011
Appl. No.:

13/324724
Inventors:

Anilkumar Kore - Austin TX, US
Shanmugasundaram Muthian - Austin TX, US
Irudaya Charles - Austin TX, US
Assignee:

Applied Biosystems, LLC - Carlsbad CA
International Classification:

C07H 21/00
B01L 3/00
C12Q 1/68
G01N 15/06
US Classification:

536 231, 536 253, 536 266, 435 61, 435325, 422 681, 422430
Abstract:

The synthesis of capped/tagged RNA, methods of use and kits providing same are contemplated. Tagged RNA permits isolation of RNA transcripts in vitro. The ability to isolate and purify capped RNA results in improved transcription and translation and provides a tool for identifying RNA-protein interactions. Such capped RNA finds use in therapeutic applications, diagnosis and prognosis and in the treatment of cancers and HIV.

5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates And Nucleic Acid Probes And Methods Of Making And Using The Same
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US Patent:

20090325158, Dec 31, 2009
Filed:

Jun 13, 2008
Appl. No.:

12/138673
Inventors:

Anilkumar R. Kore - Austin TX, US
Zhongting Hu - Los Angeles CA, US
Assignee:

APPLERA CORPORATION - Foster City CA
International Classification:

C12Q 1/68
C07H 21/04
US Classification:

435 6, 536 231, 536 256
Abstract:

5-bromo-2′-deoxy-uridine (BrdU) labeled nucleotide triphosphates and nucleic acid probes are described herein. The BrdU labeled nucleotide triphosphates include a linker between the nucleotide triphosphate and the BrdU moiety. The linker can be cleavable or non-cleavable. The nucleotide triphosphates can be a ribonucleotide triphosphates, 2′-deoxyribonucleotide triphosphates or 2′,3′-dideoxyribonucleotide triphosphates. The nucleic acid probes can be used for in situ hybridization.

5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates And Nucleic Acid Probes And Methods Of Making And Using The Same
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US Patent:

20120252030, Oct 4, 2012
Filed:

Apr 3, 2012
Appl. No.:

13/438749
Inventors:

Anilkumar R. KORE - Austin TX, US
Zhongting Hu - Los Angeles CA, US
Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:

C12Q 1/68
C07H 19/10
US Classification:

435 619, 536 256
Abstract:

5-bromo-2′-deoxy-uridine (BrdU) labeled nucleotide triphosphates and nucleic acid probes are described herein. The BrdU labeled nucleotide triphosphates include a linker between the nucleotide triphosphate and the BrdU moiety. The linker can be cleavable or non-cleavable. The nucleotide triphosphates can be a ribonucleotide triphosphates, 2′-deoxyribonucleotide triphosphates or 2′,3′-dideoxyribonucleotide triphosphates. The nucleic acid probes can be used for in situ hybridization.

Proteinase K Inhibitors, Methods And Compositions Therefor
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US Patent:

20130004941, Jan 3, 2013
Filed:

Jun 15, 2012
Appl. No.:

13/524962
Inventors:

Anilkumar R. Kore - Austin TX, US
Muthian Shanmugasundaram - Austin TX, US
Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:

C12N 9/99
C12Q 1/68
C12Q 1/70
C07K 7/06
US Classification:

435 5, 530330, 435184, 435 612
Abstract:

The synthesis, biological evaluation, and molecular modeling of alkoxysuccinyl-peptidyl-haloalkyl ketones for use as proteinase K inhibitors are described. Sample preparation processes for in situ RNA or DNA analysis using such inhibitors, methods and compositions therefor are provided.

Vehicle Records

Anilkumar Kore
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Address:

8321 Pommel Dr, Austin, TX 78759
VIN:

5FNRL38807B104865
Make:

HONDA
Model:

ODYSSEY
Year:

2007

Resumes

Director, Organic Chemistry

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Location:

Austin, TX

Industry:

Biotechnology

Work:

Thermo Fisher Scientific
Director, Organic Chemistry
Thermo Fisher Scientific
Senior Manager
Life Technologies Dec 2008 - Jan 2014
Senior Manager
Applied Bio-Systems, Inc. Mar 2006 - Nov 2008
Senior Staff Scientist, Chemistry
Ambion May 2001 - Feb 2006
Senior Scientist

Education:

University of Michigan, Ann Arbor, Michigan 2000 - 2001
Shivaji University 1992 - 1996
Doctorates, Doctor of Philosophy, Philosophy, Organic Chemistry

Skills:

Biotechnology
Chemistry
Molecular Biology
Organic Chemistry
Genomics
Dna
Life Sciences
Biochemistry
R&D
Validation
Organic Synthesis
Project Management
Laboratory
Pcr
Polymerase Chain Reaction
Research and Development
Cgmp Manufacturing
Oligonucleotide Synthesis
Nucleic Acid Chemistry
Process Chemistry
Modified Peptides
Nucleic Acid
Technology Transfer
Gmp

Languages:

English
Hindi
Marathi
German
Kannada