Alan Jay Schroit from 5130 Grape St, Houston, TX 77096, age 77

Methods And Compositions For Inducing Autoimmunity In The Treatment Of Cancers
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US Patent:

6806354, Oct 19, 2004
Filed:

Oct 9, 2001
Appl. No.:

09/974753
Inventors:

Alan J. Schroit - Houston TX
Assignee:

Board of Regents University of Texas System - Austin TX
International Classification:

C07K 1600
US Classification:

5303871, 5303881, 4242831
Abstract:

Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal. Also disclosed are methods for making phosphatidylserine conjugate compositions and their formulation for use in a variety of pharmaceutical applications including the detection and treatment of a variety of cancers and related conditions.

Β-2-Glycoprotein Is An Inhibitor Of Angiogenesis
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US Patent:

7329642, Feb 12, 2008
Filed:

Apr 2, 2003
Appl. No.:

10/406158
Inventors:

Alan Jay Schroit - Bellaire TX, US
Krishnakumar Balasubramanian - Pearland TX, US
Marya McCarty - Houston TX, US
Assignee:

Board of Regents, University of Texas System - Austin TX
International Classification:

A61K 38/00
US Classification:

514 8
Abstract:

The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked β2-Glycoprotein 1 (β2GP1) to cells associated with the tissue. The presence of β2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization into the tissue. The disclosure also provides a method for treating tumors by providing β2GP1 to the tumor.

Methods And Compositions For Inducing Autoimmunity In The Treatment Of Cancers
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US Patent:

7563446, Jul 21, 2009
Filed:

Aug 31, 2004
Appl. No.:

10/930686
Inventors:

Alan J. Schroit - Houston TX, US
Assignee:

Board of Regents, The University of Texas System - Austin TX
International Classification:

A61K 39/385
A61K 45/00
A61K 38/00
US Classification:

4241841, 4241931, 4241941, 4242781, 4242831, 514 2
Abstract:

Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal. Also disclosed are methods for making phosphatidylserine conjugate compositions and their formulation for use in a variety of pharmaceutical applications including the detection and treatment of a variety of cancers and related conditions.

Beta-2-Glycoprotein 1 Is An Inhibitor Of Angiogenesis
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US Patent:

7642234, Jan 5, 2010
Filed:

Jun 5, 2007
Appl. No.:

11/810521
Inventors:

Alan Jay Schroit - Bellaire TX, US
Krishnakumar Balasubramanian - Pearland TX, US
Marya F. McCarty - Bellaire TX, US
Assignee:

Board of Regents The University of Texas Systems - Austin TX
International Classification:

A61K 38/00
US Classification:

514 8
Abstract:

The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked β-Glycoprotein 1 (β2GP1) to cells associated with the tissue. The presence of β2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization into the tissue. The disclosure also provides a method for treating tumors by providing β2GP1 to the tumor.

Beta-2-Glycoprotein 1 Is An Inhibitor Of Angiogenesis
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US Patent:

20100226887, Sep 9, 2010
Filed:

Nov 20, 2009
Appl. No.:

12/622698
Inventors:

ALAN JAY SCHROIT - BELLAIRE TX, US
KRISHNAKUMAR BALASUBRAMANIAN - PEARLAND TX, US
MARYA MCCARTY - BELLAIRE TX, US
International Classification:

A61K 38/21
A61K 38/18
A61K 39/395
C12N 5/071
A61K 33/24
A61P 35/00
US Classification:

424 857, 514 12, 4241331, 4241301, 435325, 424649
Abstract:

The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked β2-Glycoprotein 1 (βGP1) to cells associated with the tissue. The presence of β2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization into the tissue. The disclosure also provides a method for treating tumors by providing β2GP1 to the tumor.

Methods And Compositions For Inducing Autoimmunity In The Treatment Of Cancers
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US Patent:

63003082, Oct 9, 2001
Filed:

Dec 30, 1998
Appl. No.:

9/224558
Inventors:

Alan J. Schroit - Houston TX
Assignee:

Board of Regents, The University of Texas System - Austin TX
International Classification:

A61K 3816
A61K 39385
A61K 4500
US Classification:

514 8
Abstract:

Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal. Also disclosed are methods for making phosphatidylserine conjugate compositions and their formulation for use in a variety of pharmaceutical applications including the detection and treatment of a variety of cancers and related conditions.

Pharmaceutical Compositions Consisting Of Acylated Phospholipids
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US Patent:

49833979, Jan 8, 1991
Filed:

Jul 21, 1986
Appl. No.:

6/888601
Inventors:

Alan J. Schroit - Houston TX
Rajiv Nayar - Houston TX
Assignee:

Board of Regents, University of Texas System - Houston TX
International Classification:

A61K 952
B01J 1302
US Classification:

424450
Abstract:

Liposome dispersions are prepared from (a) a synthetic phospholipid of the cephaline type in which the amino group is monoacylated with a dicarboxylic acid; (b) a synthetic phospholipid of the cephaline type; and (c) one or more compounds having pharmacological activity. The mixture optionally can contain phospholipids of natural sources and a pharmaceutical carrier solution buffered to pH 7. 0 to 7. 8.

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Alan Jay Schroit